Abstract:
Background: Atrial fibrillation (AF) increases the risk of cardiovascular complications and mortality in patients with diabetes. However, data on AF prevalence among Thai patients with type 2 diabetes (T2D) are insufficient. The specific risk factors contributing to AF among these patients also remain unclear. We determined the AF prevalence in Thai patients with T2D and identify the factors associated with AF in these patients.
Methods: This is a cross-sectional study was conducted at Burapha University Hospital. The 12-lead electrocardiography recordings of T2D patients were reviewed by a cardiologist to confirm the presence of AF. The clinical parameters, including age, sex, body-mass index (BMI), underlying medical conditions, blood pressure, heart rate, T2D duration, laboratory values, and medications were analyzed and compared between AF and non-AF patients.
Results: Altogether, 427 T2D patients (223 men and 204 women; mean age, 63.58 ? 11.62 years) were enrolled. AF prevalence among T2D patients was 10.5%. Multiple logistic regression analyses demonstrated that older age [odds ratio, 1.06; p = 0.001], increased BMI [odds ratio, 1.07; p = 0.040], and presence of heart failure [odds ratio, 4.39; p = 0.005] were independent factors associated with AF coexistence. In the subsequent multiple logistic regression analysis, no significant relationships were observed between AF and other factors, including hypertension, thyroid disease, presence of albuminuria, T2D duration, estimated glomerular filtration rate, glycated hemoglobin A1c level, and diuretic usage.
Conclusions: AF prevalence among Thai patients with T2D was 10.5%. Older age, increased BMI, and presence of heart failure were strongly associated with AF in these patients.