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Supita Sunpongsri. Effectiveness and adverse events of COP chemotherapy in feline mediastinal lymphoma naturally infected with feline leukemia virus. Master's Degree(Veterinary Clinical Studies). Kasetsart University. Office of the University Library. : Kasetsart University, 2021.
Effectiveness and adverse events of COP chemotherapy in feline mediastinal lymphoma naturally infected with feline leukemia virus
Name: Supita Sunpongsri
Classification :.LCCS: SF986.L48
LCSH:
Feline leukemia virus
LCSH:
Lymphomas in animals
LCSH:
Tumors in animals
Abstract:
Feline leukemia virus (FeLV) infection is considered a poor prognostic factor for feline lymphoma. This study investigated the prevalence of cats suffering from feline lymphoma with natural infection of the feline leukemia virus, as well as clinical signs, adverse events, and survival time after cyclophosphamide, vincristine, and prednisolone (COP) chemotherapy. This retrospective study involved 92 cats, diagnosed with mediastinal or mediastinal plus other anatomical sites of lymphoma and treated with COP chemotherapy. FeLV-antigen-positive was observed in all cats. Clinical signs and adverse events were observed after the 1st , 2 nd, and 3rd inductions. Clinical signs improved after the 3rd induction of COP chemotherapy. The response rate was 96.74% (81.52% complete response, 15.22% partial response, and 3.26% no response). The overall median survival time was 338 days (range 621,057 days). The overall response rate and median survival time of feline lymphoma that were FeLV-antigen-positive and treated with COP chemotherapy were higher than from other studies. This study found that cats aged <4 years survived longer than those aged at least 4 years. Anemia (before COP), azotemia (after 2nd induction), and elevated alanine aminotransferase (after 1st induction) were associated with an increased chance of mortality.
Kasetsart University. Office of the University Library
Address:
Bangkok
Email:
tdckulib@ku.ac.th
Name: Tassanee Jaroensong
Role:
Thesis Advisor
Created:
2021
Modified:
2025-07-20
Issued:
2025-07-20
วิทยานิพนธ์/Thesis
application/pdf
URL: https://www.lib.ku.ac.th/KUthesis/2564/supita-sun-all.pdf
CallNumber:
SF986.L48 .S87
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Veterinary Clinical Studies
Grantor: Kasetsart University
©copyrights Kasetsart University
RightsAccess:
ใช้เวลา
0.023689 วินาที
Supita Sunpongsri
| Title | Contributor | Type |
|---|---|---|
| Effectiveness and adverse events of COP chemotherapy in feline mediastinal lymphoma naturally infected with feline leukemia virus
มหาวิทยาลัยเกษตรศาสตร์ Supita Sunpongsri | Tassanee Jaroensong | วิทยานิพนธ์/Thesis |
Tassanee Jaroensong
| Title | Creator | Type and Date Create |
|---|---|---|
| The study of the clinicopathological characterization and immunohistochemical expression of CD3 and CD20 in feline nasal lymphoma
มหาวิทยาลัยเกษตรศาสตร์ Tassanee Jaroensong | Kravee Chaipoca | วิทยานิพนธ์/Thesis |
| The study of serum interleukin-8 canine mammary neoplasia
มหาวิทยาลัยเกษตรศาสตร์ Tassanee Jaroensong | Natapat Monkong | วิทยานิพนธ์/Thesis |
| Effectiveness and adverse events of COP chemotherapy in feline mediastinal lymphoma naturally infected with feline leukemia virus
มหาวิทยาลัยเกษตรศาสตร์ Tassanee Jaroensong | Supita Sunpongsri | วิทยานิพนธ์/Thesis |