Synthetic data for deep learning medical applications : generation, evaluation, and utilization

Name: Asadi, Fawad

LCSH: Generative Adversarial Networks

LCSH: Performance -- Evaluation

LCSH: Computational intelligence

LCSH: Artificial intelligenc

Abstract: Deep learning algorithms show promise in medicine for tasks like diagnosis, treatment planning, and health monitoring due to their ability to analyze diverse data and detect complex patterns, though their development is hindered by constraints such as the need for large, labeled, high-quality, and unbiased training datasets, posing challenges in their collection and preparation. Generative adversarial networks (GANs) can potentially address challenges. This research involved training progressively growing GAN (PGGAN) to generate synthetic computed tomography (CT) images of the lungs, investigating the impact of weight initialization methods on Inception v3 performance, and employing StyleGAN2 with adaptive discriminator augmentation (ADA) to generate synthetic fluid-attenuated inversion recovery (FLAIR) magnetic resonance (MRI) images with corresponding masks for deep learning training. The initial findings indicated that synthetic images generated by the PGGAN resembled real images, but there was room for improvement in GAN's performance. The subsequent study emphasized the superiority of pre-trained weights over randomly initialized models. Lastly, StyleGAN2-ADA performed well with a Fréchet inception distance (FID) score of 14.39. The addition of synthetic images did not significantly impact Unets' performance, but geometric augmentation alongside synthetic images enhanced generalization. Overall, despite their modest impact on training, synthetic data holds the potential to address data collection challenges, warranting broader exploration across other deep learning applications beyond segmentation tasks.

Rangsit University Library

Address: Pathumthani

Email: library@rsu.ac.th

Name: Jamie A. O'Reilly

Role: Advisor

Created: 2024

Modified: 2568-07-18

Issued: 2025-07-18

วิทยานิพนธ์/Thesis

application/pdf

eng

DegreeName: Doctor of Engineering

Level: Doctoral Degree

Descipline: Biomedical Engineering

Grantor: Rangsit University

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