Khwankamon Rattanatumhi. Detection of getah virus infection among domestic pigs in Thailand. Master's Degree(Animal Health Technology). Kasetsart University. Office of the University Library. : Kasetsart University, 2020.
Detection of getah virus infection among domestic pigs in Thailand
Getah virus (GETV) is a mosquito-borne RNA virus belonging to the family Togaviridae, genus Alphavirus, which is transmitted by several mosquitoes through various animal species. GETV infection causes diarrhea and death in piglets, and reproductive failure, and abortion in sows. This study is the first serological survey for GETV infection among domestic pigs in Thailand. ELISA was used to analyze 1,188 pig serum samples collected from 11 provinces of Thailand during 2017-2018, with 23.1% of the samples being positive for antiGETV antibodies. The positive ratio of anti-GETV antibodies was significantly higher in the nursery (67.9%) and older stages (84.5%) of pigs than in the finishing stage (14.2%). Furthermore, GETV was successfully isolated from one pig serum, designated as GETV strain GETV/SW/Thailand/2017, and determined the complete genome sequence (11,689 nt). Phylogenetic analysis indicated that our isolate was different from the recent GETV group spreading among pig populations in East Asia, and formed a cluster with two GETV strains, namely YN12031 (China, 2015) and LEIV16275Mar (Far East Russia, 2007). Concisely, nowadays two different GETV groups are spreading among pig populations in Asian countries.
Kasetsart University. Office of the University Library