In vitro properties of geopolymer for biomaterial applications

Name: Sarochapat Sutikulsombat

LCSH: Kasetsart University -- Theses. M.Eng. (Materials Engineering) 2018

Classification :.LCCS: TA418.9.C6

LCSH: Kasetsart University. -- Department of Materials Engineering -- Theses

LCSH: Polymeric composites

LCSH: Biomedical materials

LCSH: Inductively coupled plasma spectrometry

Abstract: This research focused on the development of metakaolin-based geopolymer investigated in order to exploit as biomaterials. The geopolymer was composed of pozzolans (metakaolin and calcium hydroxide) with additives as the solid phase and alkaline solution as the liquid phase, with a ratio of liquid to solid was 1:1 by weight. The alkaline solution was 10 M potassium hydroxide and potassium silicate which are effective for biomaterials. The additive powders were eggshell and hydroxyapatite chosen to increase calcium content; polylactic acid was added to create the porosity improve the biocompatibility of the geopolymer systems. Then, specimens were immersed in simulated body fluid (SBF) foe 7 14 21 and 28 days. The bone-like apatite layer occurred on the surface and was characterized and confirmed using SEM, XRD and FTIR. The SEM micrographs of spherical apatite particles with progressive growth day after day were observed. For XRD patterns, they presented the carbonate apatite, calcium carbonate, calcium silicate with amorphous peak. The results of the FTIR analysis exhibited the functional groups strongly supporting the XRD patterns which were detected on the surface of specimens such as phosphate and carbonate groups. The biological testing such as cytotoxicity test could determine the appropriate specimens to continue to perform for in vivo test. Furthermore, the ions leaching from specimens after immersing in SBF for 7 days would be estimated by ICP-OES. This research supported the results of apatite layer taken place on the surfaces of all geopolymers arising from immersion in SBF that these geopolymers were possibly present as a biomaterial.

Kasetsart University. Office of the University Library

Address: Bangkok

Email: tdckulib@ku.ac.th

Name: Duangrudee Chaysuwan

Role: Thesis Advisor

Created: 2018

Modified: 2025-07-08

Issued: 2025-07-08

วิทยานิพนธ์/Thesis

application/pdf

URL: https://www.lib.ku.ac.th/KUthesis/2561/sarochapat-sut-all.pdf

CallNumber: TA418.9.C6 .S27

eng

DegreeName: Master of Engineering

Level: Master's Degree

Descipline: Materials Engineering

Grantor: Kasetsart University

©copyrights Kasetsart University

ลำดับที่.	ชื่อแฟ้มข้อมูล	ขนาดแฟ้มข้อมูล	จำนวนเข้าถึง	วัน-เวลาเข้าถึงล่าสุด
1	sarochapat-sut-all.pdf	7.83 MB

ใช้เวลา

0.027786 วินาที