Effect of rheological properties on the melt extrusion of poly(L-lactide-co-ε-caprolactone) monofilament absorbable surgical sutures

Name: Kittisak Yarungsee

Organization : Chiang Mai University. Faculty of Science

Name: Montira Sriyai

Organization : Chiang Mai University. Faculty of Science

Name: Jutamas Kongsuk

Organization : Chiang Mai University. Faculty of Science

Name: Molloy, Robert

Organization : Chiang Mai University. Faculty of Science

Name: Asira Fuongfuchat

Organization : National Science and Technology Development Agency. National Metal and Materials Technology Center

Name: Winita Punyodom

Organization : Chiang Mai University. Faculty of Science

Email : winitacmu@gmail.com

keyword: poly(L-lactide-co-ε-caprolactone)

ThaSH: Biopolymers

; Absorbable sutures

ThaSH: Copolymers

Abstract: In the production of medical devices intended to be used in the human body, polymers must be of medical-grade and should not contain any stabilizers, which makes processing more challenging. The melt extrusion of high molecular weight polymers can lead to problems arising from high melt viscosity and long residence times which can in turn lead to serious thermal degradation of the polymer. Our aim in this work is to understand and compare the melt behaviour of medical-grade poly(L-lactide-co-ε-caprolactone) (PLC) in an extrusion process using a single-screw extruder. Rheology measurements are widely used to define the processing window without requiring a large amount of material. This is especially useful for expensive medical-grade polymers. The rheological properties of the PLC melt were studied in both oscillatory and steady shear testing modes in order to suggest how temperature or shear rate can be tuned to tailor the melt behaviour for melt extrusion. The combination of temperature and shear rate in an extruder is needed to modulate the polymer's melt behaviour and achieve good material properties by determining the polymer's "processing window". The results indicated that the PLC copolymer in the melt state is pseudoplastic due to the linearity of shear viscosity at low shear rate. This suggests that the copolymer melt may contain some ordered microstructures such as small crystalline domains of poly(L-lactide) which remained intact at high strain deformation.

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2020

Modified: 2024-10-21

Issued: 2024-10-21

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BibliograpyCitation : In the Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn in association, Thammasat University Faculty of Science and Technology. The Pure and Applied Chemistry International Conference 2020 (PACCON 2020) (PC192-198). Bangkok : Thammasat University

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