Curable poly(lactic acid) copolymers microbeads and its use in cosmetic application

Name: Kamonchanok Thananukul

keyword: Poly(lactic acid-co-glycidyl methacrylate)

; Suspension crosslinking

; Phase inversion emulsification

; Cosmetic application

Abstract: Biodegradable/biocompatible materials have attracted great interest in new globalization because of their degradability in natural environments. Recently, microplastics affect widely environment. Small plastics are long-lasting in nature and difficult for elimination. Among all available biodegradable materials, polylactic acid has received great attention due to its properties and providing specific functionality for developments. In this study, microbeads have been prepared from poly(lactic acid-co-glycidyl methacrylate) (P(LLA-co-GMA)) copolymers. This material can be crosslinked by employing thermo-curing reaction. Fabrications of microbeads were studied for developing their chemical and physical properties, and also tunable structures. This study proposes the two methods to improve the particle sizes. The first method is a suspension crosslinking. Effect of speed of stirring, types of surfactant and curing time are investigated. The second aimed to achieve narrow particle size distribution via a phase inversion emulsification (PIE) process. Effect of co-surfactant concentrations and the aqueous phase addition rate on efficiency of the particle formation are evaluated. Preparations of microbeads have been achieved, with spherical hollow particle. A hollow particle is applied for using booster SPF in sunscreen and cosmetic products. It significantly increases SPF value. Degradability of microbeads was investigated. Results found that microbeads can be degraded completely by hydrolytic degradation within 6 months. Microbeads morphology and their properties were characterized by different analytical techniques, such as Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC) and UV-Vis spectroscopy. In addition, this materials do not irritation on human skin. Therefore, these materials with tunable properties can be applied in many fields, especially in cosmetic application.

Thammasat University. Thammasat University Library

Address: BANGKOK

Email: preserv@tu.ac.th

Name: Pakorn Opaprakasit

Role: advisor

Created: 2017

Modified: 2021-05-28

Issued: 2021-05-28

วิทยานิพนธ์/Thesis

application/pdf

DOI: 10.14457/TU.the.2017.214

eng

DegreeName: Master of Science

Level: Master's Degree

Descipline: Engineering and Technology

Grantor: Thammasat University

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