Wanvipa Umpan. Relation between oral contraceptive use and breast cancer in women . Master's Degree(Epidemiology). Mahidol University. : Mahidol University, 2004.
Relation between oral contraceptive use and breast cancer in women
Abstract:
The main objective of the study was to determine the relationship between
oral contraceptive use and breast cancer in women. The study was conducted between
1 July and 31 December 2000, and data were obtained from female patients who
registered to Siriraj Hospital, Ramathibodi Hospital, and Rajvithi Hospital. This study
of 250 patients with historically confirmed carcinoma of the breast and 355 patients of
control obtained from the same hospital. The questionnaires were used to collect data
by interviewing patients. Data collection was also conducted by reviewing medical
records. Using a statistical and epidemiological test, the two groups were compared
results showed no association between ethnicity, place of birth, place of residence,
subject’s income, education level, occupation, current marital status, and oral
contraceptive use and breast cancer, history of irregular menstruation menopause,
hormone treatment after menopause, duration of use of oral contraceptive, age first
pregnancy, and total number of children.
There are the same indications of association with lack of knowledge on
breast cancer, (OR = 4.67, 29, 95%CI =1.31-16.73), early menarche (OR=
4.41,95%CI =1.27-15.32), age when first married at more than 25 years (OR = 9.45,
95%CI =1.38-37.55), family history of breast cancer (OR =10.84, 29, 95%CI =1.53-
76.56), and history of benign breast disease (OR =68.09, 95%CI =14.10-328.70).
Women with associated factors had higher risk associated factors, and the
most effective is the history benign breast disease.