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Vorawan Kongjinda. Chemical constituents and its biological activities from derris malaccensis . Master's Degree(Organic Chemistry). Kasetsart University. Office of the University Library. : Kasetsart University, 2004.
Chemical constituents and its biological activities from derris malaccensis
Name: Vorawan Kongjinda
LCSH:
Leguminosae
LCSH:
Derris
Classification :.LCCS: QK495.L52
Abstract:
The air-dried leaves of D. malaccensis were extracted with hexane, ethyl acetate and methanol, respectively. The ethyl acetate extract was fractionated by the use of chromatographic techniques. Two new prenylated chalcones, 2',4'-dihydroxy-4-methoxy-3'-prenylchalcone (c) and 2',4'-dihydroxy-4-methoxy-3'(2"-hydroxy-3"-methyl-3"-butenyl) chalcone (d), together with the known beta-sitosterol (b) and oblongifolic acid (a) were isolated. Their structures were elucidated by the use of 2D NMR spectroscopic methods. The structure of compound c was further confirmed by a combination of chemical transformations and X-ray crystallography. Compound c showed moderate to good activities against Staphylococus aureus, Erwinia stewartii, Bacillta cereus,Escherichia coli and Salmonella groups. Compounds c and d exhibited cytotoxic activity against human small cell lung cancer (NC1-H187) with IC50 9.1 and 9.9 micro g/ml, respectively.
Kasetsart University. Office of the University Library
Address:
กรุงเทพมหานคร (Bangkok)
Email:
tdckulib@ku.ac.th
Name: Supanna Techasakul
Role:
Thesis Advisor
Created:
2004
Issued:
2006-11-06
Modified:
2006-11-06
วิทยานิพนธ์/Thesis
application/pdf
application/pdf
application/pdf
URL: http://www.lib.ku.ac.th/KUthesis/VorawanKon/index.html
ISBN:
974-273-169-1
CallNumber:
QK495.L52 .V67
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Organic Chemistry
Grantor: Kasetsart University
©copyrights Kasetsart University
RightsAccess:
ใช้เวลา
0.096774 วินาที
Vorawan Kongjinda
| Title | Contributor | Type |
|---|---|---|
| Chemical constituents and its biological activities from derris malaccensis
มหาวิทยาลัยเกษตรศาสตร์ Vorawan Kongjinda | Supanna Techasakul | วิทยานิพนธ์/Thesis |
Supanna Techasakul